This microscope photo provided by the Mayo Clinic in August 2022 shows senescent myoblast cells. Senescent cells resist apoptosis, or programmed cell death, and characteristically get big and flat, with enlarged nuclei. They release a blend of molecules, some of which can trigger inflammation and harm other cells — and paradoxically also stimulate the growth of malignant cells and fuel cancer, says Mayo Clinic researcher Nathan LeBrasseur. (Dr. Xu Zhang/Mayo Clinic via AP)